新葡萄京娱乐场

澳门新萄京官方网站名师论坛第四十五期 | Bing Xu(徐兵) : Enzymatic Noncovalent Synthesis

来源:科技合作部 发布时间:2019-08-12 作者:科技合作部

时间2019819日(周一)上午10:00-11:30

Time10:00-11:30, Monday, Aug. 19, 2019

地点:新葡萄京娱乐场云栖校区5号楼一楼学术报告厅

Venue: Lecture Hall, 1F, Building 5, Yunqi Campus

主持人:新葡萄京娱乐场理学院讲席教授 邓力

Host: Li Deng, Chair Professor of School of Science, Westlake University 





 

 

 

 

 

 

 


主讲人/SpeakerDr. Bing Xu, Professor of Department of Chemistry, Brandeis University, USA


Bing Xu received his BS and MS from Nanjing University, and obtained his PhD from the University of Pennsylvania in 1996. Before starting his independent research at the Hong Kong University of Science and Technology on Aug 2000, he was an NIH postdoctoral fellow at Harvard University. Bing Xu was tenured as an associated professor in Jan 2006, became a full professor in July 2008 at HKUST, then moved to Brandeis University in fall of 2008. He is currently a professor in the Department of Chemistry, Brandeis University. Bing Xu was identified by THomson Reuters as "Highly-Cited Researchers in Chemistry" for 2014, 2015, and 2016.

Xu's lab focuses on the interdisciplinary frontier of materials chemistry. They integrate the knowledge and techniques in organic chemistry, materials science, surface chemistry, biochemistry, and nanotechnology to design new biofunctional materials, including nanomaterials, for the exploration in biomedicine (e.g., molecular drug delivery, cancer therapy, biomedical diagnostics, and biomimetics).

 

讲座摘要/Abstract:

Enzymatic reactions and noncovalent interactions are two fundamental non-genetic features of cells. Enzymatic noncovalent synthesis (ENS), a process that integrates enzymatic reactions and supramolecular (i.e., noncovalent) interactions for spatial organization of higher-order molecular assemblies, represents an emerging research area at the interface of physical (e.g., chemistry, physics, and nanotechnology) and biological sciences (e.g., structural biology, biochemistry, and cell biology). This talk will focus on the biological functions of ENS of small molecules, mainly short peptides. For example, pericellular and/or intracellular ENS selectively inhibits cancer cells and tumor growth; subcellular ENS delivers drugs and transfects gene expression into mitochondria; intercellular ENS enables cell morphogenesis (i.e., a 2D cell sheet become 3D cell spheroids). These studies have illustrated the use of supramolecular processes to control cellular functions for biology and medicine.



讲座联系人/Contact:

科技合作部 沈老师

shenxiaolian@westlake.edu.cn


 

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